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Ng mean and standard deviations for continuous variables and working with frequencies and percentages for categorical variables.The x test was made use of to assess the relationship in between the dose of iodine (grams) or variety of adverse impact (based on SOC and HLT) and the comparative groups.The relationship of sex, categorized age (and years), severity of adverse impact and danger things among groups had been assessed by means of your Fisher’s exact test.For mean age variations in between groups, the Wilcoxon nonparametric test for independent samples was employed.All statistical analyses were performed using SAS technique application (SAS Institute, Cary, NC).p , .was deemed statistically considerable.The study was authorized by the institutional evaluation board with the hospital.Outcomes Inside the interval between April and March , instances with adverse effects were reported for iopromide ( symptoms) compared with cases for iomeprol ( symptoms) through the interval in between January and April .The description of patient characteristics, comorbidities, diagnostic procedures and contrast dose that have been employed are detailed in Table .Within the abovementioned intervals, CT scans with contrast and urography scans (n sufferers) had been performed working with iopromide, whereas CT scans with contrast and urography scans (n) were performed utilizing iomeprol.The incidence of adverse effects was .circumstances per individuals for iopromide and .situations per patients for iomeprol.There was no statistically important difference in distribution by sex inside the compared groups (males iopromide, .; iomeprol,).The distribution by age was not statistically substantial when the typical ages of ..years for iopromide and ..years for iomeprol have been compared, nor was it statistically significant when the age was distributed with regard for the cutoff age of years, where individuals had been , years for iopromide compared with patients for iomeprol.When comorbidities (preexisting healthcare conditions) in each groups were compared, no considerable differences have been discovered, except that there were a lot more patients with an allergic history and benign prostatic hypertrophy inside the iomeprol group (p ,).In the iopromide group, situations had an allergic history [pollen , mites , nonsteroidal antiinflammatory drugs (NSAIDs) , make contact with dermatitis , salicylates , 4EGI-1 Protocol pyrazolones , sulphamides , pollen mites , NSAIDs sulphamides and flu, cold and cough medicine], whereas within the iomeprol group, cases had an allergic record [mites , pyrazolones , acetylsalicylic acid , clavulanateamoxicillin ofbjr.birjournals.orgBr J Radiol;Complete paper Acute adverse reactions to contrast mediaBJRTable .Description in the study populationDescriptionDiagnostic procedures CT, n IV urography, n Characteristics of individuals suffering an adverse drug reaction Guys Age (years), mean (SD) Age , years Danger factorcomorbidity Allergic history Asthma Prior CM reaction Renal failure Cardiac failure Hemorrhagic diathesis Coronary disease Diabetes mellitus Autoimmune illness Dehydratation Cancer COPD Asthma BPH Other people Total sufferers with premedication Route of administration Dose of iodine (g) , …UnknownIopromiden n . Iomeproln n . pvalueNS NS PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/2143897 NS IV IV.a NS NS NS NS NS NS NS NSNS NS NS .a NS NS,.a BPH, benign prostatic hypertrophy; CM, contrast media; COPD, chronic obstructive pulmonary disease; IV, intravenous; SD, regular deviation.Data are number (percentage) unless otherwise indicated.a p , sulphamides , penicillins , phenylacetic acid deriv.

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Author: heme -oxygenase