Senescence. Aging Cell 2012, 11:34549. 74. CoppJ-P, Patil C, Rodier F, Sun Y, Mu z D, Goldstein J, Nelson P, Desprez P-Y, Campisi J: Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor. PLoS Biol 2008, 6:2853868. 75. Kuilman T, Peeper DS: Senescence-messaging secretome: SMS-ing cellular anxiety. Nat Rev Cancer 2009, 9:814. 76. CoppJ-P, Desprez P-Y, Krtolica A, Campisi J: The senescence-associated secretory phenotype: the dark side of tumor suppression. Ann Rev Pathol 2010, five:9918. 77. Kang T-W, Yevsa T, Woller N, Hoenicke L, Wuestefeld T, Dauch D, Hohmeyer A, Gereke M, Rudalska R, Potapova A, Iken M, Vucur M, Weiss S, Heikenwalder M, Khan S, Gil J, Bruder D, Manns M, Schirmacher P, Tacke F, Ott M, Luedde T, Longerich T, Kubicka S, Zender L: Senescence surveillance of pre-malignant hepatocytes limits liver cancer improvement. Nature 2011, 479:54751. 78. Xue W, Zender L, Miething C, Dickins RA, Hernando E, Krizhanovsky V, Cordon-Cardo C, Lowe SW: Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas. Nature 2007, 445:65660. 79. Liu D, Hornsby P: Senescent human fibroblasts improve the early development of xenograft tumors via matrix metalloproteinase secretion. Cancer Res 2007, 67:3117126. 80. Krtolica A, Parrinello S, Lockett S, Desprez P, Campisi J: Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link among cancer and aging. Proc Nat Acad Sci U S A 2001, 98:120722077. 81. Acosta JC, Banito A, Wuestefeld T, Georgilis A, Janich P, Morton JP, Athineos D, Kang T-W, Lasitschka F, Andrulis M, Pascual G, Morris KJ, Khan S, Jin H, Dharmalingam G, Snijders AP, Carroll T, Capper D, Pritchard C, Inman GJ, Longerich T, Sansom OJ, Benitah SA, Zender L, Js G: A complicated secretory system orchestrated by the inflammasome controls paracrine senescence. Nat Cell Biol 2013, 15:97890. 82. Pahl H: Activators and target genes of Rel/NF-kappaB transcription things.Amlodipine Oncogene 1999, 18:6853866.Efavaleukin alfa 83.PMID:28038441 Barnes P, Karin M: Nuclear factor-kappaB: a pivotal transcription issue in chronic inflammatory illnesses. New Engl J Med 1997, 336:1066071. 84. Rovillain E, Mansfield L, Caetano C, Alvarez-Fernandez M, Caballero OL, Medema RH, Hummerich H, Jat PS: Activation of nuclear factor-kappa B signalling promotes cellular senescence. Oncogene 2011, 30:2356366.85. Freund A, Patil CK, Campisi J: p38MAPK is often a novel DNA damage responseindependent regulator with the senescence-associated secretory phenotype. EMBO J 2011, 30:1536548. 86. Osorio FG, Barcena C, Soria-Valles C, Ramsay AJ, de Carlos F, Cobo J, Fueyo A, Freije JMP, Lopez-Otin C: Nuclear lamina defects result in ATM-dependent NF- B activation and hyperlink accelerated aging to a systemic inflammatory response. Genes Dev 2012, 26:2311324. 87. Tilstra JS, Robinson AR, Wang J, Gregg S, Clauson CL, Reay DP, Nasto LA, St Croix CM, Usas A, Vo N, Huard J, Clemens PR, Stolz DB, Guttridge DC, Watkins SC, Garinis GA, Wang Y, Niedernhofer LJ, Robbins PD: NF-kB inhibition delays DNA damage induced senescence and aging in mice. J Clin Invest 2012, 122:2601612. 88. CoppJ-P, Rodier F, Patil CK, Freund A, Desprez P-Y, Campisi J: Tumor Suppressor and Aging Biomarker p16INK4a Induces Cellular Senescence without the Associated Inflammatory Secretory Phenotype. J Biol Chem 2011, 286:363966403. 89. Moiseeva O, Mallette F, Mukhopadhyay U, Moores A, Ferbeyre G: DNA harm signaling and p53-dependent senescence following prolon.
Heme Oxygenase heme-oxygenase.com
Just another WordPress site