Product Name :
SPDP-PEG4-NHS ester
Description:
SPDP-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS:
1334177-95-5
Molecular Weight:
559.65
Formula:
C23H33N3O9S2
Chemical Name:
2,5-dioxopyrrolidin-1-yl 1-[3-(pyridin-2-yldisulfanyl)propanamido]-3,6,9,12-tetraoxapentadecan-15-oate
Smiles :
O=C(CCSSC1=CC=CC=N1)NCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O
InChiKey:
QTVBGVZVUCIFAH-UHFFFAOYSA-N
InChi :
InChI=1S/C23H33N3O9S2/c27-19(7-18-36-37-20-3-1-2-8-25-20)24-9-11-32-13-15-34-17-16-33-14-12-31-10-6-23(30)35-26-21(28)4-5-22(26)29/h1-3,8H,4-7,9-18H2,(H,24,27)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
SPDP-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.|Product information|CAS Number: 1334177-95-5|Molecular Weight: 559.65|Formula: C23H33N3O9S2|Chemical Name: 2,5-dioxopyrrolidin-1-yl 1-[3-(pyridin-2-yldisulfanyl)propanamido]-3,6,9,12-tetraoxapentadecan-15-oate|Smiles: O=C(CCSSC1=CC=CC=N1)NCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O|InChiKey: QTVBGVZVUCIFAH-UHFFFAOYSA-N|InChi: InChI=1S/C23H33N3O9S2/c27-19(7-18-36-37-20-3-1-2-8-25-20)24-9-11-32-13-15-34-17-16-33-14-12-31-10-6-23(30)35-26-21(28)4-5-22(26)29/h1-3,8H,4-7,9-18H2,(H,24,27)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Nonyl β-D-glucopyranoside} medchemexpress|{Nonyl β-D-glucopyranoside} {Biochemical Assay Reagents}|{Nonyl β-D-glucopyranoside} Protocol|{Nonyl β-D-glucopyranoside} Description|{Nonyl β-D-glucopyranoside} supplier|{Nonyl β-D-glucopyranoside} Epigenetics} |Shelf Life: ≥12 months if stored properly.{{Sulfasalazine} medchemexpress|{Sulfasalazine} Bacterial|{Sulfasalazine} Protocol|{Sulfasalazine} In Vivo|{Sulfasalazine} manufacturer|{Sulfasalazine} Epigenetics} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23771862 |Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.|Products are for research use only. Not for human use.|