Product Name :
LUT014
Description:
LUT014 is a B-Raf inhibitor with an IC50 of 11.7 nM, and developed to reduce dose-limiting acneiform lesions associated EGFR Inhibitors treatment. Extracted from patent WO 2019026065A2 .
CAS:
2274819-46-2
Molecular Weight:
528.49
Formula:
C27H19F3N8O
Chemical Name:
6-methyl-N5-[3-(9H-purin-6-yl)pyridin-2-yl]-N1-[3-(trifluoromethoxy)phenyl]isoquinoline-1,5-diamine
Smiles :
CC1C=CC2C(NC3C=C(C=CC=3)OC(F)(F)F)=NC=CC=2C=1NC1=NC=CC=C1C1N=CN=C2NC=NC=12
InChiKey:
FZPYULHBUBXPIG-UHFFFAOYSA-N
InChi :
InChI=1S/C27H19F3N8O/c1-15-7-8-19-18(9-11-32-24(19)37-16-4-2-5-17(12-16)39-27(28,29)30)21(15)38-25-20(6-3-10-31-25)22-23-26(35-13-33-22)36-14-34-23/h2-14H,1H3,(H,31,38)(H,32,37)(H,33,34,35,36)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
LUT014 is a B-Raf inhibitor with an IC50 of 11.7 nM, and developed to reduce dose-limiting acneiform lesions associated EGFR Inhibitors treatment. Extracted from patent WO 2019026065A2 .|Product information|CAS Number: 2274819-46-2|Molecular Weight: 528.49|Formula: C27H19F3N8O|Chemical Name: 6-methyl-N5-[3-(9H-purin-6-yl)pyridin-2-yl]-N1-[3-(trifluoromethoxy)phenyl]isoquinoline-1,5-diamine|Smiles: CC1C=CC2C(NC3C=C(C=CC=3)OC(F)(F)F)=NC=CC=2C=1NC1=NC=CC=C1C1N=CN=C2NC=NC=12|InChiKey: FZPYULHBUBXPIG-UHFFFAOYSA-N|InChi: InChI=1S/C27H19F3N8O/c1-15-7-8-19-18(9-11-32-24(19)37-16-4-2-5-17(12-16)39-27(28,29)30)21(15)38-25-20(6-3-10-31-25)22-23-26(35-13-33-22)36-14-34-23/h2-14H,1H3,(H,31,38)(H,32,37)(H,33,34,35,36)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 50 mg/mL (94.Plerixafor Purity & Documentation 61 mM; Need ultrasonic).Voxilaprevir Formula |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:33023813 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
