Product Name: CCR2 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated
Applications: IF(IHC-P)
Reactivity: Human
Conjugation: ALEXA FLUOR® 555
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from mouse CCR-2
Clonality: Polyclonal
CAS NO: 913611-97-9
Product: Trimethoprim
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: C-C chemokine receptor type 2; C-C CKR-2; CC-CKR-2; CCR-2; CCR2; Monocyte chemoattractant protein 1 receptor; MCP-1-R; CMKBR2
Background: This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. [provided by RefSeq, Mar 2009].
PubMed ID:http://jpet.aspetjournals.org/content/305/1/131
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