Product Name: CD14 Polyclonal Antibody, Cy5 Conjugated
Applications: FCM, IF(IHC-P)
Reactivity: Human, Mouse, Rat
Conjugation: Cy5
Host: Rabbit
Sourcr: KLH conjugated synthetic peptide derived from mouse CD14
Clonality: Polyclonal
CAS NO: 130693-82-2
Product: PCI-32765 (Racemate)
Isotype: IgG
Concentration: 1ug/ul
Purification: Purified by Protein A.
Storage: Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Synonyms: Monocyte differentiation antigen CD14; Myeloid cell-specific leucine-rich glycoprotein; CD14
Background: In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the MD-2/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules (By similarity).
PubMed ID:http://jpet.aspetjournals.org/content/306/3/1027
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